Benzene

Benzene

SCHEMBL6064566

C.CC.CC.CC.CC.N=C=O.N=C=O.c1ccccc1.c1ccccc1

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL9561229 1.00 TSHR (0.31) TSHRCASP1
Benzene SCHEMBL28339975 1.00 TSHR (0.31) TSHRCASP1
Benzene SCHEMBL408741 0.96 TSHR (0.33) TSHRCASP1
Benzene SCHEMBL9390629 0.96 TSHR (0.33) TSHRCASP1
Benzene SCHEMBL27624654 0.96 TSHR (0.33) TSHRCASP1
Benzene SCHEMBL9622706 0.96 TSHR (0.33) TSHRCASP1
Benzene SCHEMBL29206608 0.96 TSHR (0.33) TSHRCASP1
Benzene SCHEMBL9863896 0.96 TSHR (0.33) TSHRCASP1
Benzene SCHEMBL25280208 0.91 TP53 (0.30) TSHR
Benzene SCHEMBL190412 0.91 TP53 (0.30) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4511077-A1 BONE REPAIR COMPOSITIONS COMPRISING POLYTHIOURETHANE AND USES THEREOF Smith&Nephew, Inc. (US) 2025-02-26 EP claimed
WO-2023205141-A1 BONE REPAIR COMPOSITIONS COMPRISING POLYTHIOURETHANE AND USES THEREOF SMITH & NEPHEW, INC. (US) 2023-10-26 WO claimed
US-9084827-B2 Biodegradable polyurethane/urea compositions POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2015-07-21 US claimed
US-20140099277-A1 BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2014-04-10 US claimed
US-20130150964-A1 BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2013-06-13 US claimed
US-20250262347-A1 BONE REPAIR COMPOSITIONS COMPRISING POLYTHIOURETHANE AND USES THEREOF SMITH & NEPHEW INC (US) 2025-08-21 US disclosed
EP-4511077-A1 BONE REPAIR COMPOSITIONS COMPRISING POLYTHIOURETHANE AND USES THEREOF Smith&Nephew, Inc. (US) 2025-02-26 EP disclosed
WO-2023205141-A1 BONE REPAIR COMPOSITIONS COMPRISING POLYTHIOURETHANE AND USES THEREOF SMITH & NEPHEW, INC. (US) 2023-10-26 WO disclosed
EP-3042920-A1 BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS Polynovo Biomaterials Pty Limited (AU) 2016-07-13 EP disclosed
CN-1774460-B Biodegradable polyurethane/urea compositions COMMW SCIENT IND RES ORG 2010-04-21 CN disclosed
CN-1774460-A Biodegradable polyurethane/urea compositions COMMW SCIENT IND RES ORG (AU) 2006-05-17 CN disclosed
EP-1572339-A4 BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS COMMW SCIENT IND RES ORG (AU) 2006-04-19 EP disclosed
EP-1572339-A2 BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-09-14 EP disclosed
WO-2004009227-A2 BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140099277-A1 BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS PUF60, UMPS, COL2A1 TSHR 4785/4885CASP1 1283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.