Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B14 | Q9BPX1 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836704 | 0.92 | KMT2A (0.51) | HSD17B14KMT2AKDM4EPIM1METAP2 | |
| SCHEMBL3860500 | 0.91 | HSD17B14 (0.52) | HSD17B14KDM4ECNR2MGAMALDH1A1 | |
| SCHEMBL3825336 | 0.79 | KDM4E (0.53) | HSD17B14KMT2AKDM4EPIM1METAP2 | |
| SCHEMBL8746411 | 0.72 | CNR2 (0.47) | HSD17B14KMT2AKDM4ECNR2MGAM | |
| SCHEMBL28605670 | 0.72 | CNR2 (0.62) | KMT2AKDM4ECNR2MGAMALDH1A1 | |
| SCHEMBL9335143 | 0.72 | CNR2 (0.48) | HSD17B14KMT2AKDM4ECNR2MGAM | |
| SCHEMBL7245263 | 0.72 | PTPN1 (0.44) | HSD17B14KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL28443611 | 0.72 | MGAM (0.61) | KMT2AKDM4ECNR2MGAMNCF1 | |
| SCHEMBL8617775 | 0.71 | MGAM (0.49) | HSD17B14KMT2AKDM4ECNR2MGAM | |
| SCHEMBL7243815 | 0.70 | PIM1 (0.57) | KDM4EPIM1ALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129134-A1 | SYNERGIC COMBINATIONS COMPRISING A STYRYLQUINOLINE COMPOUND AND OTHER HIV INFECTION THERAPEUTIC AGENTS | BIOALLIANCE PHARMA (FR) | 2006-12-07 | — | — | WO | claimed |