Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IGFBP5 | P24593 | 3/20 | 0.40 |
| ▸ | IGFBP3 | P17936 | 3/20 | 0.40 |
| ▸ | IGFBP1 | P08833 | 1/20 | 0.40 |
| ▸ | IGFBP2 | P18065 | 1/20 | 0.40 |
| ▸ | IGFBP4 | P22692 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235575 | 0.86 | KDM4E (0.44) | PTPN1KDM4EPOLBGAAMAPT | |
| SCHEMBL3860500 | 0.76 | HSD17B14 (0.52) | KDM4EGAAMAPTHSD17B14ALDH1A1 | |
| SCHEMBL2806839 | 0.75 | MGAM (0.58) | PTPN1KDM4EPOLBAKR1C3AKR1C2 | |
| SCHEMBL7243815 | 0.75 | PIM1 (0.57) | KDM4EPOLBGAAMAPTCA12 | |
| SCHEMBL28061749 | 0.74 | MAPT (0.53) | PTPN1KDM4EPOLBGAAMAPT | |
| SCHEMBL6064587 | 0.72 | HSD17B14 (0.45) | KDM4EGAAMAPTL3MBTL1KMT2A | |
| SCHEMBL17433761 | 0.69 | NR4A1 (0.52) | PTPN1KDM4EPOLBCA12CA1 | |
| SCHEMBL31466752 | 0.69 | NR4A1 (0.52) | PTPN1KDM4EPOLBCA12CA1 | |
| SCHEMBL7893778 | 0.68 | ACMSD (0.56) | PTPN1KDM4ECA12CA1CA2 | |
| SCHEMBL10520040 | 0.67 | GRIN2D (0.50) | PTPN1KDM4EPOLBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670377-B1 | Inhibitory properties of human immunodeficiency virus integrase | CENTRE NATIONAL DE LA RECHERCHE (FR) | 2003-12-30 | — | — | US | disclosed |