Oxyquinoline

Oxyquinoline

SCHEMBL6064682

O=Nc1ccc2ccccc2c1O.Oc1cccc2cccnc12

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.58
KDM4E B2RXH2 9/20 0.58
TDP1 Q9NUW8 7/20 0.58
ALDH1A1 P00352 5/20 0.58
L3MBTL1 Q9Y468 5/20 0.58
RAB9A P51151 3/20 0.58
NPC1 O15118 3/20 0.58
NPSR1 Q6W5P4 2/20 0.58
XBP1 P17861 1/20 0.58
MMP2 P08253 1/20 0.57
CHRM1 P11229 1/20 0.57
TSHR P16473 1/20 0.57
COMT P21964 1/20 0.57
ADRA1A P35348 1/20 0.57
METAP2 P50579 1/20 0.57
METAP1 P53582 1/20 0.57
HDAC8 Q9BY41 1/20 0.57
ALOX12 P18054 2/20 0.54
LMNA P02545 5/20 0.51
KMT2A Q03164 7/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7897309 0.81 KDM4E (0.56) MAPTKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL104099 0.81 KMT2A (0.54) MAPTKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL27796148 0.79 KMT2A (0.53) MAPTKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL29424253 0.79 KMT2A (0.53) MAPTKDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL6136591 0.79 KMT2A (0.53) MAPTKDM4ETDP1ALDH1A1L3MBTL1
Oxyquinoline SCHEMBL28110568 0.77 TSHR (0.81) MAPTKDM4ETDP1ALDH1A1L3MBTL1
Nitrous Acid SCHEMBL9724629 0.77 KMT2A (0.51) MAPTKDM4ETDP1ALDH1A1L3MBTL1
Oxyquinoline SCHEMBL599825 0.77 TSHR (0.95) MAPTKDM4ETDP1ALDH1A1L3MBTL1
Oxyquinoline SCHEMBL4593830 0.77 TSHR (0.95) MAPTKDM4ETDP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL6865586 0.76 L3MBTL1 (0.97) MAPTKDM4ETDP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006023779-A2 METAL EXTRACTION IN LIQUID OR SUPERCRITICAL-FLUID SOLVENTS IDAHO RESEARCH FOUNDATION, INC. (US) 2006-03-02 WO disclosed
CN-1061383-C Method and apparatus for back-extracting metal chelates IDOHO RES FOUNDATION INC (US) 2001-01-31 CN disclosed