Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 4/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyquinoline SCHEMBL6064682 | 0.81 | MAPT (0.58) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL18434322 | 0.80 | LMNA (0.55) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL8581634 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL4063648 | 0.75 | MMP2 (0.63) | KDM4EALDH1A1MAPTTDP1MMP2 | |
| SCHEMBL3685011 | 0.74 | CCR1 (0.57) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL12663631 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL8401989 | 0.74 | HSP90AA1 (0.54) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| Phenanthroline SCHEMBL8150927 | 0.73 | CCR1 (0.94) | KDM4EALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL27872555 | 0.73 | ALDH1A1 (0.77) | KDM4EALDH1A1MAPTTDP1MMP2 | |
| Phenanthroline SCHEMBL4318850 | 0.72 | LMNA (0.80) | KDM4EALDH1A1MAPTTDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225275-B1 | ACTIVATION OF OXIDOREDUCTASES FOR BLEACHING FABRICS DURING WASHING | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. | 2001-05-01 | — | — | US | disclosed |