SCHEMBL6064706

SCHEMBL6064706

Cl[Zr](Cl)C1C(N2c3ccccc3Sc3ccccc32)=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.35
BCHE P06276 8/20 0.33
HDAC6 Q9UBN7 1/20 0.31
ACHE P22303 1/20 0.31
NOX1 Q9Y5S8 1/20 0.31
POLB P06746 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5603351 0.78 MAOA (0.36) MAOABCHEHDAC6ACHENOX1
SCHEMBL5602478 0.77 MAOA (0.35) MAOABCHEHDAC6ACHENOX1
SCHEMBL5601765 0.77 MAOA (0.35) MAOABCHEHDAC6ACHENOX1
Hydrochloric Acid SCHEMBL6064703 0.77 MAOA (0.37) MAOABCHEHDAC6ACHENOX1
Hydrochloric Acid SCHEMBL5601755 0.75 MAOA (0.36) MAOABCHEHDAC6ACHENOX1
Hydrochloric Acid SCHEMBL5603348 0.75 MAOA (0.36) MAOABCHEHDAC6ACHENOX1
Hydrochloric Acid SCHEMBL5602467 0.75 MAOA (0.36) MAOABCHEHDAC6ACHENOX1
SCHEMBL5602211 0.72
SCHEMBL6064727 0.71 MAOA (0.36) MAOABCHEACHENOX1
SCHEMBL6065343 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP disclosed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO disclosed