Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 10/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6064703 | 0.81 | MAOA (0.37) | MAOABCHEHDAC6ACHENOX1 | |
| Hydrochloric Acid SCHEMBL5601755 | 0.79 | MAOA (0.36) | MAOABCHEHDAC6ACHENOX1 | |
| Hydrochloric Acid SCHEMBL5603348 | 0.79 | MAOA (0.36) | MAOABCHEHDAC6ACHENOX1 | |
| Hydrochloric Acid SCHEMBL5603172 | 0.79 | MAOA (0.31) | MAOA | |
| Hydrochloric Acid SCHEMBL5603386 | 0.78 | — | — | |
| SCHEMBL5603351 | 0.77 | MAOA (0.36) | MAOABCHEHDAC6ACHENOX1 | |
| SCHEMBL5601765 | 0.75 | MAOA (0.35) | MAOABCHEHDAC6ACHENOX1 | |
| SCHEMBL6064706 | 0.75 | MAOA (0.35) | MAOABCHEHDAC6ACHENOX1 | |
| SCHEMBL5602478 | 0.75 | MAOA (0.35) | MAOABCHEHDAC6ACHENOX1 | |
| Hydrochloric Acid SCHEMBL5601398 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |