Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 10/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603210 | 0.87 | MAOA (0.42) | NOX1MAOABCHEACHEKDM1A | |
| SCHEMBL6064931 | 0.86 | ALDH1A1 (0.38) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL6064248 | 0.84 | BCHE (0.34) | NOX1BCHEKMT2A | |
| SCHEMBL6064252 | 0.82 | HSP90AA1 (0.33) | — | |
| SCHEMBL6065338 | 0.81 | NOX1 (0.35) | NOX1MAOABCHEACHEMEN1 | |
| SCHEMBL6064959 | 0.76 | ALDH1A1 (0.35) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL6064976 | 0.74 | BCHE (0.33) | BCHEKMT2A | |
| SCHEMBL6064840 | 0.72 | HSP90AA1 (0.31) | — | |
| SCHEMBL5601814 | 0.70 | ALDH1A1 (0.41) | MAOABCHEACHEMEN1KMT2A | |
| SCHEMBL14244233 | 0.69 | MAOA (0.54) | NOX1MAOABCHEACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735354-A1 | HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | Exxonmobil Chemical Company Inc. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005105864-A1 | HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-11-10 | — | — | WO | disclosed |