SCHEMBL6065579

SCHEMBL6065579

NSn1ccc(=O)[nH]c1=O

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.54
DDB1 Q16531 1/20 0.44
PKM P14618 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
DUT P33316 3/20 0.32
SLC28A1 O00337 1/20 0.32
SLC28A2 O43868 1/20 0.32
SLC29A1 Q99808 1/20 0.32
SLC28A3 Q9HAS3 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8652641 0.78 CRBN (0.48) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL2111850 0.78 CRBN (0.48) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL14638096 0.78 CRBN (0.48) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL665845 0.78 CRBN (0.54) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL4347792 0.77 CRBN (0.47) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL7546865 0.74 CRBN (0.44) CRBNDDB1PKMALDH1A1LMNA
SCHEMBL8656959 0.74 CRBN (0.48) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL8952355 0.72 CRBN (0.52) CRBNDDB1ALDH1A1DUT
SCHEMBL954608 0.71 CRBN (0.46) CRBNDDB1PKMDUT
SCHEMBL710129 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101443399-A Stabilizer composition for halogenated polymers with improved initial color and improved color retention BAERLOCHER GMBH (DE) 2009-05-27 CN claimed
CN-1500118-A Use of substituted biaromatic beta-diketone as stabilising agent of halogenated polymers and resulting polymer �޵��ǻ�ѧ��˾ 2004-05-26 CN claimed
CN-101124269-B Composition for the stabilization of halogenated polymers comprising a beta-dicarbonyl compound RHONE POULENC CHIMIE 2012-05-23 CN disclosed
CN-101443399-A Stabilizer composition for halogenated polymers with improved initial color and improved color retention BAERLOCHER GMBH (DE) 2009-05-27 CN disclosed
CN-101124269-A Halogenated polymer stabilising ingredient containing a beta-dicarbonyl compound RHONE POULENC CHIMIE (FR) 2008-02-13 CN disclosed
EP-1560878-B1 THERMALLY STABILISED PVC COMPOSITIONS LAMBERTI SPA (IT) 2006-05-17 EP disclosed
EP-1560878-A1 THERMALLY STABILISED PVC COMPOSITIONS Lamberti Spa (IT) 2005-08-10 EP disclosed
EP-1174461-B1 Thermally stabilized PVC compositions LAMBERTI SPA (IT) 2004-10-27 EP disclosed
US-6790885-B2 CHLORINE CONTAINING POLYMER COMPOSITIONS CONTAINING STABILIZERS WHICH IMPART GOOD THERMAL STABILITY. PVC COMPOSITIONS AND, IN PARTICULAR, FLEXIBLE PVC COMPOSITIONS CONTAINING STABILIZERS WHICH ARE OLIGOMERIC AND/OR POLYMERIC LAMBERTI SPA (IT) 2004-09-14 US disclosed
WO-2004046236-A1 THERMALLY STABILISED PVC COMPOSITIONS LAMBERTI SPA (IT) 2004-06-03 WO disclosed
CN-1500118-A Use of substituted biaromatic beta-diketone as stabilising agent of halogenated polymers and resulting polymer �޵��ǻ�ѧ��˾ 2004-05-26 CN disclosed
US-20030109607-A1 Thermally stabilized polyvinyl chloride compositions LAMBERTI SPA (IT) 2003-06-12 US disclosed
EP-1174461-A1 Thermally stabilized PVC compositions LAMBERTI S.p.A. (IT) 2002-01-23 EP disclosed
CN-1178228-A Rigid PVC stabilised with N, N-dimethyl-6-aminouracils CIBA GEIGY AG (CH) 1998-04-08 CN disclosed