SCHEMBL954608

SCHEMBL954608

CCCSn1ccc(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 4/20 0.46
PKM P14618 1/20 0.41
DDB1 Q16531 1/20 0.38
DUT P33316 3/20 0.35
GPR84 Q9NQS5 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiourea SCHEMBL29139741 0.91 CRBN (0.39) CRBNPKMDDB1DUT
SCHEMBL4347792 0.89 CRBN (0.47) CRBNPKMDDB1DUT
SCHEMBL16671886 0.88 GPR84 (0.43) CRBNPKMGPR84
SCHEMBL8653846 0.87 GPR84 (0.46) CRBNPKMGPR84
SCHEMBL8656959 0.85 CRBN (0.48) CRBNPKMDDB1DUT
Methimazole SCHEMBL8813156 0.83 CRBN (0.39) CRBNPKMDUTGPR84
Propylthiouracil SCHEMBL5493721 0.82 LPO (0.59) CRBNGPR84
SCHEMBL665845 0.75 CRBN (0.54) CRBNPKMDDB1DUT
SCHEMBL28362679 0.74 CRBN (0.40) CRBNPKMDDB1DUT
SCHEMBL2714279 0.72 CRBN (0.47) CRBNPKMDDB1DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114105888-B Eutectic crystal of propylthiouracil and nutrient micromolecule with antioxidant activity and preparation method thereof 天津大学 2023-12-01 CN claimed
CN-114190328-A Construction method and application of non-alcoholic fatty liver disease animal model based on NLRP3 gene knockout 杭州市西溪医院 2022-03-18 CN claimed
CN-114105888-A Eutectic crystal of propylthiouracil and small nutrient molecules with antioxidant activity and preparation method thereof 天津大学 2022-03-01 CN claimed
CN-109745139-B Construction method of nutrition and defense atherosclerotic animal model 青岛市中医医院(青岛市海慈医院、青岛市康复医学研究所) 2021-08-03 CN claimed
CN-111821066-A Non-stick coating and method for making same 皮考逊公司 2020-10-27 CN claimed
US-10364337-B2 Inhibition of amine oxidation HUNTSMAN PETROCHEMICAL LLC (US) 2019-07-30 US claimed
EP-2521746-B1 INHIBITION OF AMINE OXIDATION HUNTSMAN PETROCHEMICAL LLC (US) 2019-03-13 EP claimed
CN-108348497-A Method for treating mucositis 株式会社Enzychem生命科学 2018-07-31 CN claimed
US-20160130213-A1 INHIBITION OF AMINE OXIDATION HUNTSMAN PETROCHEMICAL LLC (US) 2016-05-12 US claimed
EP-2464342-B1 PHARMACEUTICAL FORMULATIONS AGAINST DRUG MISUSE DEBREGEAS ET ASSOCIES PHARMA (FR) 2014-02-26 EP claimed
EP-2521746-A1 INHIBITION OF AMINE OXIDATION Huntsman Petrochemical LLC (US) 2012-11-14 EP claimed
US-20120271026-A1 INHIBITION OF AMINE OXIDATION HUNTSMAN PETROCHEMICAL LLC 2012-10-25 US claimed
WO-2011084865-A1 INHIBITION OF AMINE OXIDATION HUNTSMAN PETROCHEMICAL LLC (US) 2011-07-14 WO claimed
CN-101460060-A Compositions and methods for topical treatment of tar-responsive skin disorders TRISTRATA INC (US) 2009-06-17 CN claimed
EP-1809381-A2 USE OF COMPOUNDS FOR THE PREVENTION OF DRUG-INDUCED CELL TOXICITY Recepticon ApS (DK) 2007-07-25 EP claimed
WO-2006037335-A2 USE OF COMPOUNDS FOR THE PREVENTION OF DRUG-INDUCED CELL TOXICITY RECEPTICON APS (DK) 2006-04-13 WO claimed
EP-0934339-A1 IgG IMMUNOGLOBULINS AND F(ab') 2? FRAGMENTS THEREOF, SPECIFIC FOR DRUGS AND METABOLITES THEREOF, AND THEIR USE FOR DETOXIFICATION PURPOSES DOX-AL ITALIA S.p.A. (IT) 1999-08-11 EP claimed
WO-1997049732-A1 IgG IMMUNOGLOBULINS AND F(ab')2 FRAGMENTS THEREOF, SPECIFIC FOR DRUGS AND METABOLITES THEREOF, AND THEIR USE FOR DETOXIFICATION PURPOSES DOX-AL ITALIA S.P.A. (IT) 1997-12-31 WO claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP disclosed
US-4018786-A HYPOCHOLESTEROLEMIC CENTRE D'ETUDES POUR L'INDUSTRIE PHARMACEUTIQUE (FR) 1977-04-19 US disclosed