Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28760710 | 0.85 | HSP90AA1 (0.37) | SMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL6065962 | 0.83 | LPAR1 (0.36) | GAA | |
| SCHEMBL5494271 | 0.82 | RIPK2 (0.38) | ALDH1A1GAAJAK2JAK1JAK3 | |
| SCHEMBL6065937 | 0.81 | GAA (0.35) | ALDH1A1GAA | |
| SCHEMBL28760707 | 0.81 | MEN1 (0.35) | ALDH1A1GAAMAPK1KMOLMNA | |
| SCHEMBL3116816 | 0.77 | GAA (0.35) | GAAMAPK1KMOLMNA | |
| SCHEMBL28760706 | 0.76 | ALDH1A1 (0.36) | ALDH1A1GAA | |
| SCHEMBL6065935 | 0.76 | GAA (0.35) | GAA | |
| SCHEMBL6065063 | 0.74 | MEN1 (0.30) | — | |
| SCHEMBL6065184 | 0.74 | TSHR (0.33) | SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663245-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005027909-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2005-03-31 | — | — | WO | disclosed |