Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620811 | 0.84 | NPC1 (0.45) | LPAR1KMT2AMAPTHTTGAA | |
| SCHEMBL6065728 | 0.83 | SMN1; SMN2 (0.33) | GAA | |
| SCHEMBL4204205 | 0.80 | ALDH1A1 (0.41) | LPAR1KMT2AVNN1MAPTRIPK2 | |
| SCHEMBL6065837 | 0.79 | LPAR1 (0.37) | LPAR1KMT2AVNN1MAPTNTRK1 | |
| SCHEMBL3113554 | 0.78 | KCNN4 (0.37) | LPAR1VNN1KCNN4HTTCYP1A2 | |
| SCHEMBL17853170 | 0.77 | KDM4C (0.42) | LPAR1VNN1MAPTKCNN4GAA | |
| SCHEMBL3119092 | 0.75 | LPAR1 (0.38) | LPAR1KMT2AVNN1NTRK1HTT | |
| Carbamic Acid SCHEMBL3119184 | 0.74 | BRD4 (0.32) | LPAR1KMT2AVNN1MAPTNTRK1 | |
| SCHEMBL3105963 | 0.74 | ALDH1A1 (0.41) | LPAR1KMT2AMAPTHTTGAA | |
| Carbamic Acid SCHEMBL3119239 | 0.74 | BRD4 (0.32) | LPAR1KMT2AVNN1MAPTNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663245-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| EP-1556389-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2005027909-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2005-03-31 | — | — | WO | disclosed |
| WO-2004039814-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2004-05-13 | — | — | WO | disclosed |