Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.33 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 8/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065534 | 0.94 | SPHK1 (0.36) | BBOX1CHRNB4CHRNA3CHRNA7CHRNA10 | |
| SCHEMBL6064932 | 0.91 | SPHK2 (0.33) | BBOX1CHRNB4CHRNA3CHRNA7CHRNA10 | |
| SCHEMBL6065134 | 0.88 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL6065701 | 0.87 | CYP1A2 (0.30) | CYP1A2 | |
| SCHEMBL6066116 | 0.86 | CYP1A2 (0.32) | CYP1A2 | |
| SCHEMBL6064884 | 0.85 | — | — | |
| SCHEMBL6066199 | 0.84 | CYP1A2 (0.30) | CYP1A2 | |
| SCHEMBL6065400 | 0.84 | CYP1A2 (0.30) | CYP1A2 | |
| SCHEMBL6065111 | 0.82 | DNM1 (0.31) | — | |
| SCHEMBL21837354 | 0.82 | BBOX1 (0.48) | BBOX1CHRNB4CHRNA3CHRNA7CHRNA10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101940-B2 | Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2006-09-05 | — | — | US | disclosed |
| US-20030013913-A1 | Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins | EQUISTAR CHEMICALS, LP | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013913-A1 | Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins | SCO2, CNOT1, CYC1 | BBOX1 542/4885CHRNB4 3338/4885CHRNA3 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.