Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425021 | 0.90 | CYP1A2 (0.34) | LPAR1NTRK1LMNA | |
| SCHEMBL6065063 | 0.88 | MEN1 (0.30) | — | |
| SCHEMBL27639665 | 0.88 | LPAR1 (0.33) | LPAR1NTRK1 | |
| SCHEMBL28755600 | 0.84 | NTRK1 (0.39) | LPAR1NTRK1LMNA | |
| SCHEMBL3123213 | 0.83 | NTRK1 (0.35) | LPAR1NTRK1LMNA | |
| SCHEMBL6427254 | 0.82 | LPAR1 (0.33) | LPAR1NTRK1 | |
| SCHEMBL6386231 | 0.82 | CYP3A4 (0.36) | LMNA | |
| SCHEMBL5498848 | 0.81 | NTRK1 (0.36) | LPAR1NTRK1 | |
| SCHEMBL6427256 | 0.80 | BCHE (0.35) | LPAR1 | |
| SCHEMBL6065837 | 0.80 | LPAR1 (0.37) | LPAR1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663245-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005027909-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2005-03-31 | — | — | WO | disclosed |