Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065092 | 0.90 | ITGA4 (0.35) | BCHERORCCKS1BSKP1SKP2 | |
| SCHEMBL3123213 | 0.89 | NTRK1 (0.35) | MEN1GAAKMT2ALPAR1 | |
| SCHEMBL3121409 | 0.89 | CTSS (0.37) | RORCCKS1BSKP1SKP2AKT1 | |
| SCHEMBL5492718 | 0.88 | BCHE (0.40) | BCHECKS1BSKP1SKP2IDO1 | |
| SCHEMBL6065295 | 0.87 | IDO1 (0.33) | BCHERORCCKS1BSKP1SKP2 | |
| SCHEMBL3113414 | 0.86 | AKT1 (0.35) | RORCCKS1BSKP1SKP2AKT1 | |
| SCHEMBL3106076 | 0.85 | AKT1 (0.37) | BCHECKS1BSKP1SKP2IDO1 | |
| SCHEMBL5500423 | 0.84 | IDO1 (0.44) | BCHECKS1BSKP1SKP2IDO1 | |
| SCHEMBL3114661 | 0.84 | AAK1 (0.40) | RORCCKS1BSKP1SKP2AKT1 | |
| SCHEMBL27661812 | 0.83 | SIGMAR1 (0.39) | BCHERORCCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100343260-C | Cephem compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 2007-10-17 | — | — | CN | disclosed |
| CN-1852715-A | Cephem compounds | ASTELLAS PHARMA INC (JP) | 2006-10-25 | — | — | CN | disclosed |
| CN-1708502-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-12-14 | — | — | CN | disclosed |
| EP-1556389-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039814-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2004-05-13 | — | — | WO | disclosed |