Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3119092 | 0.90 | LPAR1 (0.38) | LPAR1KDM4ENTRK1BRD4BRD9 | |
| SCHEMBL6425412 | 0.89 | ALDH1A1 (0.37) | LPAR1KDM4ENTRK1BRD4BRD9 | |
| SCHEMBL5500962 | 0.88 | ADRA2C (0.39) | LPAR1GAANTRK1BRD4BRD9 | |
| SCHEMBL6065834 | 0.88 | LPAR1 (0.36) | LPAR1NTRK1BRD4BRD9BPTF | |
| SCHEMBL6425423 | 0.86 | HPGD (0.40) | KDM4EGAANTRK1MAPTKMT2A | |
| SCHEMBL3111828 | 0.86 | NTRK1 (0.36) | LPAR1GAANTRK1BRD4BRD9 | |
| Carbamic Acid SCHEMBL5499998 | 0.86 | CA1 (0.40) | LPAR1KDM4EGAANTRK1BRD4 | |
| SCHEMBL3105963 | 0.84 | ALDH1A1 (0.41) | LPAR1KDM4EGAAMAPTKMT2A | |
| SCHEMBL5497720 | 0.84 | KDM4E (0.36) | LPAR1KDM4EGAANTRK1BRD4 | |
| Carbamic Acid SCHEMBL3119184 | 0.84 | BRD4 (0.32) | LPAR1KDM4EGAANTRK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1852715-A | Cephem compounds | ASTELLAS PHARMA INC (JP) | 2006-10-25 | — | — | CN | disclosed |
| EP-1663245-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005027909-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2005-03-31 | — | — | WO | disclosed |