Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.71 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.71 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.43 |
| ▸ | PI4KA | P42356 | 6/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 6/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 6/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29529372 | 0.84 | ADORA2A (1.00) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| SCHEMBL8566 | 0.84 | ADORA2A (1.00) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| Pyrophosphoric Acid SCHEMBL6065977 | 0.81 | ADORA2A (0.44) | ADORA2AADORA1 | |
| SCHEMBL8342350 | 0.76 | ADORA2A (0.81) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| Adenine SCHEMBL1035725 | 0.75 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBTSHR | |
| Niacinamide SCHEMBL3281893 | 0.70 | ADORA2A (0.58) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| Triphosphate SCHEMBL502620 | 0.70 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBTSHR | |
| Triphosphate SCHEMBL29941501 | 0.70 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBTSHR | |
| Adenine SCHEMBL29843997 | 0.69 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBTSHR | |
| SCHEMBL931970 | 0.68 | ADORA2A (0.61) | ADORA2AADORA1NUDT1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711626-A2 | NUCLEIC ACID SEQUENCING BY RAMAN MONITORING OF UPTAKE OF NUCLEOTIDES DURING MOLECULAR REPLICATION | INTEL CORPORATION (US) | 2006-10-18 | — | — | EP | disclosed |
| US-20050202468-A1 | Nucleic acid sequencing by Raman monitoring of uptake of nucleotides during molecular replication | INTEL CORPORATION | 2005-09-15 | — | — | US | disclosed |
| WO-2005066369-A2 | NUCLEIC ACID SEQUENCING BY RAMAN MONITORING OF UPTAKE OF NUCLEOTIDES DURING MOLECULAR REPLICATION | INTEL CORPORATION (US) | 2005-07-21 | — | — | WO | disclosed |
| US-20050147979-A1 | Nucleic acid sequencing by Raman monitoring of uptake of nucleotides during molecular replication | INTEL CORPORATION (US) | 2005-07-07 | — | — | US | disclosed |