Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL6065977

Nc1ncnc2[nH]c(Br)nc12.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.44

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.44
ADORA1 P30542 4/20 0.44
ENPP1 P22413 3/20 0.33
ENPP3 O14638 1/20 0.33
P2RY2 P41231 1/20 0.33
FGFR1 P11362 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
ADORA2B P29275 3/20 0.33
FBP1 P09467 1/20 0.32
P2RX1 P51575 2/20 0.31
P2RX3 P56373 2/20 0.31
P2RX2 Q9UBL9 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ENTPD1 P49961 1/20 0.31
MAP4K4 O95819 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8565 0.84 ADORA2A (0.58) ADORA2AADORA1ADORA2BADORA3
Pyrophosphoric Acid SCHEMBL6065979 0.81 ADORA2A (0.71) ADORA2AADORA1
SCHEMBL8342338 0.75 ADORA2A (0.49) ADORA2AADORA1ADORA2BADORA3
Adenine SCHEMBL1035724 0.74 PI4KA (0.36) ADORA1ENPP1ENPP3P2RY2FGFR1
Niacinamide SCHEMBL3281888 0.69 F7 (0.52) ADORA2AADORA1
SCHEMBL6065982 0.67 ADORA2A (0.48) ADORA2AADORA1ENPP1ENPP3ADORA2B
Adenine SCHEMBL1035725 0.67 PI4KA (0.69) ENPP1CYP3A4
Phosphoric Acid SCHEMBL21065570 0.67 LMNA (0.34) ADORA2AADORA1FGFR1SLC22A6FBP1
SCHEMBL42336 0.67 PIK3CG (0.42) ADORA2AADORA1
SCHEMBL42313 0.66 ADORA2A (0.42) ADORA2AADORA1ADORA2BADORA3MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1711626-A2 NUCLEIC ACID SEQUENCING BY RAMAN MONITORING OF UPTAKE OF NUCLEOTIDES DURING MOLECULAR REPLICATION INTEL CORPORATION (US) 2006-10-18 EP disclosed
US-20050202468-A1 Nucleic acid sequencing by Raman monitoring of uptake of nucleotides during molecular replication INTEL CORPORATION 2005-09-15 US disclosed
WO-2005066369-A2 NUCLEIC ACID SEQUENCING BY RAMAN MONITORING OF UPTAKE OF NUCLEOTIDES DURING MOLECULAR REPLICATION INTEL CORPORATION (US) 2005-07-21 WO disclosed
US-20050147979-A1 Nucleic acid sequencing by Raman monitoring of uptake of nucleotides during molecular replication INTEL CORPORATION (US) 2005-07-07 US disclosed