Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.81 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.81 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.47 |
| ▸ | PI4KA | P42356 | 8/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 8/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 8/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29529372 | 0.90 | ADORA2A (1.00) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| SCHEMBL8566 | 0.90 | ADORA2A (1.00) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| SCHEMBL843169 | 0.90 | ADORA2A (0.61) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| Pyrophosphoric Acid SCHEMBL6065979 | 0.76 | ADORA2A (0.71) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| SCHEMBL8342338 | 0.72 | ADORA2A (0.49) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| SCHEMBL42314 | 0.71 | ADORA2A (0.66) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| SCHEMBL3799507 | 0.71 | ADORA2A (0.37) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| SCHEMBL29400753 | 0.71 | ADORA2A (0.66) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| SCHEMBL1059581 | 0.70 | NUDT1 (0.68) | ADORA2AADORA1NUDT1PI4KAPI4K2B | |
| SCHEMBL30109321 | 0.70 | NUDT1 (0.68) | ADORA2AADORA1NUDT1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872243-A | Caged nucleotides | MOLECULAR PROBES, INC. (US) | 1999-02-16 | — | — | US | claimed |