Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6066919 | 0.88 | MEN1 (0.50) | KMT2AMEN1ATMSMN1; SMN2HTT | |
| SCHEMBL524586 | 0.84 | KMT2A (0.64) | KMT2AMEN1ATMSMN1; SMN2GAA | |
| SCHEMBL31369624 | 0.76 | S1PR1 (0.55) | KMT2AMEN1ATMSMN1; SMN2FFAR1 | |
| SCHEMBL13101471 | 0.75 | KMT2A (0.56) | KMT2AMEN1ATMSMN1; SMN2HTT | |
| SCHEMBL3196104 | 0.75 | MEN1 (0.62) | KMT2AMEN1ATMSMN1; SMN2GAA | |
| SCHEMBL7327740 | 0.74 | L3MBTL1 (0.54) | GAAKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL5652930 | 0.74 | SMN1; SMN2 (0.59) | KMT2AMEN1ATMSMN1; SMN2HTT | |
| SCHEMBL13113227 | 0.73 | SMN1; SMN2 (0.66) | KMT2AMEN1ATMSMN1; SMN2GAA | |
| SCHEMBL9544789 | 0.73 | SMN1; SMN2 (0.61) | KMT2AMEN1ATMSMN1; SMN2GAA | |
| SCHEMBL4459745 | 0.72 | SMN1; SMN2 (0.59) | KMT2AMEN1ATMSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709195-A2 | CELL TRANSFECTING FORMULATIONS OF SMALL INTERFERING RNA, RELATED COMPOSITIONS AND METHODS OF MAKING AND USE | CHIRON CORPORATION (US) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005060697-A2 | CELL TRANSFECTING FORMULATIONS OF SMALL INTERFERING RNA, RELATED COMPOSITIONS AND METHODS OF MAKING AND USE | CHIRON CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |