Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067393 | 0.83 | TSHR (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL5357916 | 0.83 | ZDHHC20 (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL6067443 | 0.83 | TSHR (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL1659840 | 0.80 | ZDHHC20 (0.56) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL3138226 | 0.80 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL19712275 | 0.79 | SMN1; SMN2 (0.34) | ACACB | |
| SCHEMBL29043132 | 0.79 | ZDHHC20 (0.59) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28017724 | 0.77 | ZDHHC20 (0.40) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28056045 | 0.76 | ZDHHC20 (0.51) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28017219 | 0.76 | TSHR (0.34) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006087079-A1 | COMPOSITIONS CURED BY MICHAEL ADDITION REACTION | Consortium für elektrochemische Industrie GmbH (DE) | 2006-08-24 | — | — | WO | disclosed |