SCHEMBL6067393

SCHEMBL6067393

C=CC(=O)NC[Si](C)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
TGM2 P21980 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6067443 0.85 TSHR (0.43) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL6067405 0.83 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL5321292 0.81 TSHR (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL114687 0.81 ZDHHC20 (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28017322 0.77 ZDHHC20 (0.39) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL448048 0.76 ALDH1A1 (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL2461687 0.75 ALOX15 (0.34) ALDH1A1TDP1
SCHEMBL477439 0.75 EPHX1 (0.39) TSHR
SCHEMBL5357916 0.74 ZDHHC20 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL6067477 0.74 THRB (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006087079-A1 COMPOSITIONS CURED BY MICHAEL ADDITION REACTION Consortium für elektrochemische Industrie GmbH (DE) 2006-08-24 WO disclosed