SCHEMBL6067451

SCHEMBL6067451

CC(C)(C1C=C(CCO[Si](C)(C)C)c2ccccc21)C1C=C(CCO[Si](C)(C)C)c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6066756 0.79
SCHEMBL6445149 0.77 HTR6 (0.39) HTR6
SCHEMBL6066734 0.77 HTR6 (0.33) HTR6
SCHEMBL6067259 0.76 HTR6 (0.40) HTR6
SCHEMBL8158527 0.76 ACHE (0.39) HTR6
SCHEMBL7718899 0.75 HTR6 (0.36) HTR6
SCHEMBL6475443 0.75 HTR6 (0.38) HTR6
SCHEMBL8158524 0.75 PTPN1 (0.41) HTR6
SCHEMBL6067048 0.74
SCHEMBL6067276 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7148173-B2 Catalytic systems for the polymerization and copolymerization of alpha-olefins REPSOL QUIMICA, S.A. (ES) 2006-12-12 US claimed
US-7148173-B2 Catalytic systems for the polymerization and copolymerization of alpha-olefins REPSOL QUIMICA, S.A. (ES) 2006-12-12 US disclosed
EP-0953581-B1 Catalytic systems for the polymerization and copolymerization of alpha-olefins REPSOL QUIMICA SA (ES) 2004-01-07 EP disclosed
US-20030191013-A1 CATALYTIC SYSTEMS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF ALPHA-OLEFINS REPSOL QUIMICA S.A. (ES) 2003-10-09 US disclosed
EP-0953581-A1 Catalytic systems for the polymerization and copolymerization of alpha-olefins REPSOL QUIMICA S.A. (ES) 1999-11-03 EP disclosed