Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6067005 | 0.89 | MEN1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6066885 | 0.87 | ALDH1A1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6067204 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL6066765 | 0.85 | MEN1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6067555 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL6067309 | 0.76 | MEN1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6067339 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL6067134 | 0.72 | MEN1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6067524 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL6067158 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148173-B2 | Catalytic systems for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA, S.A. (ES) | 2006-12-12 | — | — | US | claimed |
| US-7148173-B2 | Catalytic systems for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA, S.A. (ES) | 2006-12-12 | — | — | US | disclosed |
| EP-0953581-B1 | Catalytic systems for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA SA (ES) | 2004-01-07 | — | — | EP | disclosed |
| US-20030191013-A1 | CATALYTIC SYSTEMS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF ALPHA-OLEFINS | REPSOL QUIMICA S.A. (ES) | 2003-10-09 | — | — | US | disclosed |
| EP-0953581-A1 | Catalytic systems for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA S.A. (ES) | 1999-11-03 | — | — | EP | disclosed |