Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821988 | 0.98 | CES2 (0.48) | CES2MAPTLMNAMEN1FAAH | |
| SCHEMBL6416630 | 0.92 | CES2 (0.41) | CES2MAPTLMNAMEN1FAAH | |
| SCHEMBL6591638 | 0.85 | MEN1 (0.53) | CES2MAPTLMNAMEN1FAAH | |
| SCHEMBL9074143 | 0.85 | MEN1 (0.53) | CES2MAPTLMNAMEN1FAAH | |
| SCHEMBL4939835 | 0.84 | ALDH1A1 (0.40) | CES2LMNAKMT2A | |
| SCHEMBL2989445 | 0.83 | CES2 (0.64) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL11509841 | 0.83 | CES2 (0.64) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL11852256 | 0.83 | KMT2A (0.36) | CES2MAPTKMT2A | |
| SCHEMBL10541848 | 0.82 | MEN1 (0.50) | CES2MAPTLMNAMEN1FAAH | |
| SCHEMBL28302659 | 0.81 | CES2 (0.48) | CES2MAPTLMNAMEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |