Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067711 | 0.89 | CYP4F2 (0.40) | CYP4F2CYP4A11TSHRABCB11CYP1A2 | |
| SCHEMBL6067676 | 0.85 | MEN1 (0.44) | CYP4F2CYP4A11TSHRPPARAALDH1A1 | |
| SCHEMBL6067613 | 0.83 | SOAT1 (0.41) | CYP4F2CYP4A11TSHRABCB11CYP1A2 | |
| SCHEMBL2036323 | 0.78 | ALDH1A1 (0.50) | CYP4F2CYP4A11TSHRABCB11CYP1A2 | |
| SCHEMBL6067685 | 0.77 | ALDH1A1 (0.44) | CYP4F2CYP4A11TSHRABCB11CYP1A2 | |
| SCHEMBL6067632 | 0.76 | MMP8 (0.49) | CYP4F2CYP4A11MMP8ALDH1A1MEN1 | |
| SCHEMBL6067614 | 0.74 | HDAC3 (0.42) | TSHRPPARAALDH1A1MEN1KMT2A | |
| SCHEMBL2097977 | 0.72 | CYP4F2 (0.44) | CYP4F2CYP4A11TSHRABCB11CYP1A2 | |
| SCHEMBL27691346 | 0.72 | CYP4F2 (0.44) | CYP4F2CYP4A11TSHRABCB11CYP1A2 | |
| SCHEMBL18799245 | 0.71 | CYP4F2 (0.40) | CYP4F2CYP4A11TSHRABCB11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |