Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067608 | 0.93 | ALDH1A1 (0.48) | MMP8ALDH1A1RECQLPIN1MAPT | |
| SCHEMBL6067632 | 0.85 | MMP8 (0.49) | MMP8ALDH1A1RECQLPIN1MAPT | |
| SCHEMBL6067620 | 0.80 | CES1 (0.48) | ALDH1A1MAPTSMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL6067718 | 0.79 | ALDH1A1 (0.46) | MMP8ALDH1A1RECQLPIN1MAPT | |
| SCHEMBL6067645 | 0.78 | ALDH1A1 (0.53) | MMP8ALDH1A1RECQLPIN1MAPT | |
| SCHEMBL18113275 | 0.74 | ALDH1A1 (0.50) | MMP8ALDH1A1RECQLPIN1MAPT | |
| SCHEMBL6067702 | 0.74 | ALDH1A1 (0.49) | MMP8ALDH1A1RECQLPIN1MAPT | |
| SCHEMBL6067613 | 0.74 | SOAT1 (0.41) | MMP8ALDH1A1PIN1ABCB11CYP1A2 | |
| SCHEMBL8710582 | 0.73 | MMP8 (0.79) | MMP8ALDH1A1RECQLPIN1MAPT | |
| SCHEMBL1492859 | 0.73 | MMP8 (0.65) | MMP8ALDH1A1RECQLPIN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |