Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20346330 | 1.00 | MEN1 (0.50) | MEN1KMT2ACYP2C19MMP8CTDSP1 | |
| SCHEMBL6067717 | 0.91 | MMP8 (0.45) | MEN1KMT2ACYP2C19MMP8CTDSP1 | |
| SCHEMBL6067634 | 0.83 | L3MBTL1 (0.61) | MEN1KMT2ACYP2C19LMNAL3MBTL1 | |
| SCHEMBL28695526 | 0.83 | KMT2A (0.49) | MEN1KMT2ACYP2C19MMP8CTDSP1 | |
| SCHEMBL28698361 | 0.83 | KMT2A (0.49) | MEN1KMT2ACYP2C19MMP8CTDSP1 | |
| SCHEMBL28852029 | 0.83 | KMT2A (0.49) | MEN1KMT2ACYP2C19MMP8CTDSP1 | |
| SCHEMBL11106384 | 0.80 | SMN1; SMN2 (0.47) | MEN1KMT2ACYP2C19MMP8CTDSP1 | |
| SCHEMBL11106418 | 0.80 | SMN1; SMN2 (0.47) | MEN1KMT2ACYP2C19MMP8CTDSP1 | |
| SCHEMBL9796645 | 0.79 | MEN1 (0.49) | MEN1KMT2ACYP2C19CTDSP1LMNA | |
| SCHEMBL9796641 | 0.79 | MEN1 (0.49) | MEN1KMT2ACYP2C19CTDSP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |