Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067677 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AMEN1CYP19A1 | |
| SCHEMBL6067635 | 0.93 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2AMEN1CYP19A1 | |
| SCHEMBL14194362 | 0.86 | KMT2A (0.66) | ALDH1A1MAPTKMT2AMEN1CYP19A1 | |
| SCHEMBL6067609 | 0.84 | CES2 (0.51) | ALDH1A1MAPTKMT2AMEN1CYP19A1 | |
| SCHEMBL9721404 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AMEN1CYP19A1 | |
| SCHEMBL21734206 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AMEN1CYP19A1 | |
| SCHEMBL9721402 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AMEN1CYP19A1 | |
| SCHEMBL3398770 | 0.83 | KMT2A (0.58) | ALDH1A1MAPTKMT2AMEN1CYP19A1 | |
| SCHEMBL18709565 | 0.83 | MAPT (0.50) | ALDH1A1MAPTKMT2AMEN1CYP19A1 | |
| SCHEMBL20179813 | 0.83 | MAPT (0.50) | ALDH1A1MAPTKMT2AMEN1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |