SCHEMBL6067692

SCHEMBL6067692

C=C(C)C(C)(C(=O)O)C(=O)OC(C)CC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6067721 0.77 MAPT (0.40) MAPTNPSR1
SCHEMBL3371032 0.76 MAPT (0.35) MAPTNPSR1
SCHEMBL11374202 0.74 MAPT (0.34) MAPT
SCHEMBL18489636 0.74 MAPT (0.34) MAPTNPSR1
SCHEMBL6067640 0.73 ALDH1A1 (0.39) MAPT
SCHEMBL2976274 0.73 PRKCA (0.44) MAPTNPSR1
SCHEMBL2479166 0.73 PRKCA (0.44) MAPTNPSR1
SCHEMBL2980891 0.73 PRKCA (0.44) MAPTNPSR1
SCHEMBL3353497 0.73 MAPT (0.36) MAPTNPSR1
SCHEMBL17848832 0.73 HMGCR (0.37) MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006100606-A2 PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION WARNER-LAMBERT COMPANY LLC (US) 2006-09-28 WO disclosed