Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067703 | 1.00 | CA2 (0.41) | CA2MAPK1SLC15A1PLA2G2CGPR84 | |
| SCHEMBL5516454 | 0.88 | HDAC1 (0.39) | GPR84ACE2POLBALDH1A1TSHR | |
| SCHEMBL20218222 | 0.88 | HDAC1 (0.39) | GPR84ACE2POLBALDH1A1TSHR | |
| SCHEMBL6250281 | 0.79 | CA2 (0.52) | CA2MAPK1GPR84CA1ACE2 | |
| SCHEMBL6251102 | 0.79 | CA2 (0.52) | CA2MAPK1GPR84CA1ACE2 | |
| SCHEMBL3500277 | 0.79 | CA2 (0.52) | CA2MAPK1GPR84CA1ACE2 | |
| SCHEMBL6067684 | 0.79 | MME (0.42) | ACE2ALDH1A1TSHR | |
| SCHEMBL6067688 | 0.79 | MME (0.42) | ACE2ALDH1A1TSHR | |
| SCHEMBL6827612 | 0.77 | CA2 (0.56) | CA2MAPK1PLA2G2CGPR84CA1 | |
| Bicarbonate SCHEMBL6442737 | 0.75 | CA2 (0.52) | CA2MAPK1SLC15A1GPR84CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |