Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 6/20 | 0.34 |
| ▸ | HTR7 | P34969 | 6/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414579 | 0.70 | KMO (0.36) | — | |
| SCHEMBL6068463 | 0.68 | ELANE (0.34) | ELANEARPIK3CA | |
| SCHEMBL14445212 | 0.66 | PTGIR (0.38) | — | |
| SCHEMBL5420279 | 0.65 | PTGIR (0.40) | — | |
| SCHEMBL6068787 | 0.64 | — | — | |
| SCHEMBL5426976 | 0.62 | TSHR (0.36) | — | |
| SCHEMBL13723813 | 0.62 | SYK (0.46) | ELANEARPIK3CASYKMAT2A | |
| SCHEMBL15129357 | 0.62 | ELANE (0.47) | ELANEARSYKMAT2A | |
| SCHEMBL77156 | 0.62 | SYK (0.46) | ELANEARPIK3CASYKMAT2A | |
| SCHEMBL6068784 | 0.62 | PTGIR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |