Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068966 | 0.72 | SCN9A (0.36) | — | |
| SCHEMBL5425256 | 0.72 | S1PR2 (0.31) | — | |
| SCHEMBL6068607 | 0.68 | ELANE (0.38) | ELANEPIK3CAAR | |
| SCHEMBL6068751 | 0.67 | SMPD3 (0.33) | — | |
| SCHEMBL5416501 | 0.65 | APP (0.31) | — | |
| SCHEMBL5421732 | 0.64 | APP (0.30) | — | |
| SCHEMBL6068852 | 0.63 | PLAU (0.33) | — | |
| SCHEMBL6068717 | 0.63 | CDK1 (0.35) | — | |
| SCHEMBL5423142 | 0.61 | S1PR2 (0.30) | — | |
| SCHEMBL5433722 | 0.60 | CDK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |