Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068674 | 1.00 | MTNR1A (0.40) | MTNR1AMTNR1BTK1LMNACYP1A2 | |
| SCHEMBL6068667 | 1.00 | MTNR1A (0.40) | MTNR1AMTNR1BTK1LMNACYP1A2 | |
| SCHEMBL6068595 | 0.85 | MTNR1A (0.36) | MTNR1AMTNR1BTK1LMNACYP1A2 | |
| SCHEMBL6068591 | 0.85 | MTNR1A (0.36) | MTNR1AMTNR1BTK1LMNACYP1A2 | |
| SCHEMBL6068598 | 0.85 | MTNR1A (0.36) | MTNR1AMTNR1BTK1LMNACYP1A2 | |
| SCHEMBL6068590 | 0.78 | CYP1A2 (0.54) | MTNR1AMTNR1BLMNACYP1A2AGTR1 | |
| SCHEMBL6068589 | 0.78 | CYP1A2 (0.54) | MTNR1AMTNR1BLMNACYP1A2AGTR1 | |
| SCHEMBL6068594 | 0.78 | CYP1A2 (0.54) | MTNR1AMTNR1BLMNACYP1A2AGTR1 | |
| SCHEMBL773403 | 0.77 | MTNR1A (0.46) | MTNR1AMTNR1BLMNACYP1A2AGTR1 | |
| SCHEMBL2111572 | 0.75 | KIF11 (0.50) | TK1LMNATSHRCTSKKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109234-B2 | Benzoxathiepine derivatives and their use as medicines | PIERRE FABRE MEDICAMENT (FR) | 2006-09-19 | — | — | US | disclosed |
| EP-1370547-B1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PF MEDICAMENT (FR) | 2004-09-15 | — | — | EP | disclosed |
| US-20040127552-A1 | Benzoaxathiepin derivatives and their use as medicines | PIERRE FABRE MEDICAMENT (FR) | 2004-07-01 | — | — | US | disclosed |
| EP-1370547-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002081464-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127552-A1 | Benzoaxathiepin derivatives and their use as medicines | CYP4A11, CYP3A4, CYP4F11 | MTNR1A 234/4885MTNR1B 185/4885TK1 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.