Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 2/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5714471 | 0.99 | TXNRD1 (0.46) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL5713925 | 0.83 | TXNRD1 (0.45) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL5713987 | 0.82 | TXNRD1 (0.44) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL5713981 | 0.82 | TXNRD1 (0.44) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL5713984 | 0.82 | TXNRD1 (0.44) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL5713550 | 0.81 | GSTP1 (0.45) | KMT2AMEN1MAPT | |
| SCHEMBL5713782 | 0.80 | GSTP1 (0.47) | KMT2AMEN1MAPT | |
| SCHEMBL5713935 | 0.78 | TXNRD1 (0.47) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL5713954 | 0.78 | TXNRD1 (0.50) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL5713853 | 0.77 | TXNRD1 (0.49) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040139563-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | Wella GmbH (DE) | 2004-07-22 | — | — | US | claimed |
| US-20040139562-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | Wella GmbH (DE) | 2004-07-22 | — | — | US | claimed |
| US-20030171594-A1 | 7-Nitro-2,1,3-benzoxadiazole derivatives and 7-nitro-2,1,3-benzthiadiazole derivatives and dyes, which contain these compounds and which are used for dying keratin fibers | Wella GmbH (DE) | 2003-09-11 | — | — | US | claimed |
| US-7083656-B2 | 7-nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | WELLA AG (DE) | 2006-08-01 | — | — | US | disclosed |
| US-6908492-B2 | 7-nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-06-21 | — | — | US | disclosed |
| US-6869454-B2 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-03-22 | — | — | US | disclosed |
| US-20040226108-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | Wella GmbH (DE) | 2004-11-18 | — | — | US | disclosed |
| US-20040139563-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | Wella GmbH (DE) | 2004-07-22 | — | — | US | disclosed |
| US-20040139562-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | Wella GmbH (DE) | 2004-07-22 | — | — | US | disclosed |
| US-6726730-B2 | HAIR DYES WHICH ARE READILY SOLUBLE IN WATER AND DISTINGUISHED BY UNIFORM ABSORPTION BEHAVIOR AND HIGH WASHING STABILITY; ENABLE DYEING UNDER GENTLE AND SKIN-COMPATIBLE CONDITIONS | WELLA AKTIENGESELLSCHAFT (DE) | 2004-04-27 | — | — | US | disclosed |
| US-20030171594-A1 | 7-Nitro-2,1,3-benzoxadiazole derivatives and 7-nitro-2,1,3-benzthiadiazole derivatives and dyes, which contain these compounds and which are used for dying keratin fibers | Wella GmbH (DE) | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040226108-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | KRT18, NUCB2, NDUFA3 | TXNRD1 704/4885TXNRD3 789/4885TXNRD2 277/4885 |
| US-20040139562-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | KRT18, CNN2, TUBB1 | TXNRD1 474/4885TXNRD3 512/4885TXNRD2 441/4885 |
| US-20030171594-A1 | 7-Nitro-2,1,3-benzoxadiazole derivatives and 7-nitro-2,1,3-benzthiadiazole derivatives and dyes, which contain these compounds and which are used for dying keratin fibers | KRT18, CASP5, CASP7 | TXNRD1 356/4885TXNRD3 616/4885TXNRD2 278/4885 |
| US-20040139563-A1 | 7-Nitro-2,1,3-benzoxadiazole and 7-nitro-2,1,3-benzthiadiazole derivatives, as well dyeing agents for keratin fibers containing these compounds | KRT18, CNN2, TUBB1 | TXNRD1 474/4885TXNRD3 512/4885TXNRD2 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.