Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068784 | 0.98 | PTGIR (0.38) | PTGIRTBXAS1ADORA2AHDAC1 | |
| SCHEMBL6068838 | 0.89 | MEN1 (0.34) | — | |
| SCHEMBL6068729 | 0.88 | PTGIR (0.49) | PTGIRTBXAS1 | |
| SCHEMBL5420279 | 0.81 | PTGIR (0.40) | PTGIRTBXAS1ADORA2AHDAC1HDAC6 | |
| SCHEMBL14445212 | 0.80 | PTGIR (0.38) | PTGIRTBXAS1ADORA2AHDAC1 | |
| SCHEMBL6068684 | 0.80 | LMNA (0.36) | — | |
| SCHEMBL6069026 | 0.78 | APP (0.34) | — | |
| SCHEMBL6068476 | 0.78 | TLR7 (0.31) | — | |
| SCHEMBL6068678 | 0.77 | APP (0.35) | — | |
| SCHEMBL6068957 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |