Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068728 | 0.86 | GAA (0.41) | LMNAKDM4ESMN1; SMN2NPC1MITF | |
| SCHEMBL6068838 | 0.83 | MEN1 (0.34) | LMNAKDM4EMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL6068949 | 0.83 | LMNA (0.34) | LMNAKDM4EMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL6068784 | 0.81 | PTGIR (0.38) | — | |
| SCHEMBL6068801 | 0.80 | PTGIR (0.40) | — | |
| SCHEMBL6068655 | 0.79 | ABL1 (0.31) | LMNAKDM4EMAPK1TSHRABL1 | |
| SCHEMBL6068547 | 0.79 | LMNA (0.31) | LMNAKDM4EMAPK1TSHR | |
| SCHEMBL1803436 | 0.78 | TSHR (0.38) | LMNAKDM4EMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL6068957 | 0.76 | — | — | |
| SCHEMBL5424153 | 0.75 | LMNA (0.35) | LMNAKDM4EMAPK1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |