Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069244 | 0.84 | TLR7 (0.43) | CYP1A2CYP2C9CYP2C19TLR7L3MBTL1 | |
| SCHEMBL6069500 | 0.83 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1TDP1KDM4EMAPT | |
| SCHEMBL6069318 | 0.78 | ALDH1A1 (0.37) | TLR7ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL6069298 | 0.77 | ALDH1A1 (0.36) | TLR7ALDH1A1KDM4EMAPTTP53 | |
| SCHEMBL27603756 | 0.74 | ALDH1A1 (0.42) | CYP1A2CYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL31172404 | 0.73 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19ALDH1A1TDP1 | |
| SCHEMBL2846218 | 0.73 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19ALDH1A1TDP1 | |
| SCHEMBL1029928 | 0.72 | CYP1A2 (0.66) | CYP1A2CYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL29684634 | 0.72 | CYP1A2 (0.66) | CYP1A2CYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL23352277 | 0.72 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074243-B2 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-11 | — | — | US | claimed |
| CN-1529691-A | N-benzyl-m-phenylenediamine derivatives and colorants containing these compounds | P&G | 2004-09-15 | — | — | CN | claimed |
| US-20030182735-A1 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | US | claimed |
| US-7074243-B2 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20030182735-A1 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030182735-A1 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | KRT18, VIM, KPNB1 | CYP1A2 2895/4885CYP2C9 2928/4885CYP2C19 3985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.