Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.60 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.54 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10859843 | 0.86 | PDCD1 (0.53) | VSIRPDCD1CD274 | |
| SCHEMBL11957878 | 0.85 | MPO (0.55) | MPOSCN8ANOS1TAAR1 | |
| SCHEMBL2257962 | 0.84 | TAAR1 (0.61) | MPONOS1TAAR1KDM4E | |
| SCHEMBL30573214 | 0.83 | MPO (0.58) | MPOSCN8ANOS1TAAR1KDM4E | |
| SCHEMBL28353482 | 0.83 | MPO (0.58) | MPOSCN8ANOS1TAAR1KDM4E | |
| SCHEMBL5020048 | 0.82 | MAOB (0.61) | — | |
| SCHEMBL5390719 | 0.81 | SCN8A (0.57) | MPOSCN8ANOS1TAAR1KDM4E | |
| SCHEMBL6069821 | 0.81 | MPO (0.56) | MPOSCN8ANOS1TAAR1KDM4E | |
| SCHEMBL10480660 | 0.81 | TAAR1 (0.58) | MPOSCN8ANOS1TAAR1KDM4E | |
| SCHEMBL10440878 | 0.81 | MPO (0.56) | MPOSCN8ANOS1TAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102675240-B | 4-substitute-2-hydroxy morpholine-3-ketone and preparation method thereof | ZHEJIANG HISUN PHARM CO LTD | 2015-01-14 | — | — | CN | disclosed |
| US-7091199-B1 | Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1216249-B1 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMA INC (US) | 2003-11-19 | — | — | EP | disclosed |
| EP-1216249-A2 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019832-A2 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |