Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 3/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 2/20 | 0.47 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CSK | P41240 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294259 | 0.90 | PDCD1 (0.50) | PDCD1CD274SMN1; SMN2CHRM2GSR | |
| SCHEMBL7023370 | 0.90 | ENPP2 (0.47) | PDCD1CD274SMN1; SMN2CHRM2MEN1 | |
| SCHEMBL30821501 | 0.89 | GAA (0.53) | PDCD1CD274SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2670053 | 0.88 | SLC2A4 (0.59) | PDCD1CD274SMN1; SMN2KMT2A | |
| SCHEMBL10855431 | 0.87 | KDM4E (0.57) | CHRM2MEN1KMT2ATDP1CXCR4 | |
| SCHEMBL14492270 | 0.86 | PDCD1 (0.54) | PDCD1CD274SMN1; SMN2GSRVSIR | |
| SCHEMBL9415942 | 0.86 | CHRM2 (0.71) | CHRM2 | |
| SCHEMBL6069853 | 0.86 | MPO (0.60) | PDCD1CD274VSIR | |
| SCHEMBL16619429 | 0.86 | CYP1A2 (0.61) | PDCD1CD274SMN1; SMN2 | |
| SCHEMBL1497920 | 0.86 | PDCD1 (0.46) | PDCD1CD274SMN1; SMN2CHRM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590288-A | REVERSIBLE ABSORPTION OF CARBON MONOXIDE | EXXON RESEARCH AND ENGINEERING CO. (US) | 1986-05-20 | — | — | US | disclosed |