SCHEMBL6069864

SCHEMBL6069864

Nc1ccc(Oc2cccc(N)c2)cc1.Nc1ccccc1-c1ccccc1N

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.67
ALDH1A1 P00352 8/20 0.63
MAPT P10636 4/20 0.63
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
MITF O75030 1/20 0.63
GAA P10253 1/20 0.63
GFER P55789 1/20 0.63
NLRP1 Q9C000 1/20 0.63
NOD2 Q9HC29 1/20 0.63
MAOA P21397 1/20 0.57
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
NLRP3 Q96P20 1/20 0.56
ATM Q13315 1/20 0.50
CYP3A4 P08684 2/20 0.48
TSHR P16473 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15876510 0.87 ALDH1A1 (0.83) MAOBALDH1A1MAPTMEN1KMT2A
SCHEMBL8432560 0.87 ALDH1A1 (0.83) MAOBALDH1A1MAPTMEN1KMT2A
SCHEMBL29366093 0.87 ALDH1A1 (0.83) MAOBALDH1A1MAPTMEN1KMT2A
SCHEMBL63373 0.87 ALDH1A1 (0.83) MAOBALDH1A1MAPTMEN1KMT2A
SCHEMBL710424 0.87 ALDH1A1 (0.83) MAOBALDH1A1MAPTMEN1KMT2A
4-Phenoxyaniline SCHEMBL1066956 0.85 MAOB (0.84) MAOBALDH1A1MAPTMEN1KMT2A
SCHEMBL8836596 0.85 ALDH1A1 (0.87) MAOBALDH1A1MAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL8645103 0.85 ALDH1A1 (0.79) MAOBALDH1A1MAPTMEN1KMT2A
SCHEMBL29558001 0.85 ALDH1A1 (0.87) MAOBALDH1A1MAPTMEN1KMT2A
Ammonia Solution, Strong SCHEMBL4657846 0.85 ALDH1A1 (0.79) MAOBALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9926408-B2 Preparation of imide oligomers via concurrent reactive extrusion POLYONE CORPORATION (US) 2018-03-27 US disclosed
US-20160215095-A1 PREPARATION OF IMIDE OLIGOMERS VIA CONCURRENT REACTIVE EXTRUSION POLYONE CORPORATION (US) 2016-07-28 US disclosed
WO-2015048065-A1 PREPARATION OF IMIDE OLIGOMERS VIA CONCURRENT REACTIVE EXTRUSION POLYONE CORPORATION (US) 2015-04-02 WO disclosed
US-20140135447-A1 PREPARATION OF IMIDE OLIGOMERS POLYONE CORPORATION (US) 2014-05-15 US disclosed
WO-2013006621-A2 PREPARATION OF IMIDE OLIGOMERS POLYONE CORPORATION (US) 2013-01-10 WO disclosed
US-RE43880-E1 Solvent free low-melt viscosity imide oligomers and thermosetting polymide composites THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2012-12-25 US disclosed
US-7015304-B1 reacting specific aromatic dianhydrides such as 2,3,3',4'-biphenyltetracarboxylic dianydride, and aromatic diamines containing one or two benzene rings with a reactive monofunctional endcap such as phenylethynyl phthalic anhydride; melt processability; transfer molding with fiber preforms THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2006-03-21 US disclosed