SCHEMBL60703

SCHEMBL60703

c1ccc(-c2ccccc2C2CCCCC2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.63
BRD4 O60885 1/20 0.47
PTPN5 P54829 3/20 0.46
PTPN2 P17706 1/20 0.46
CYP11B2 P19099 2/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
ADRA2A P08913 1/20 0.44
ADRA1D P25100 1/20 0.44
ADRA1A P35348 1/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CHRNB2 P17787 1/20 0.42
CHRNA4 P43681 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27912155 1.00 PTGS2 (0.63) PTGS2BRD4PTPN5PTPN2CYP11B2
Cyclohexane SCHEMBL9787037 1.00 PTGS2 (0.63) PTGS2BRD4PTPN5PTPN2CYP11B2
SCHEMBL28154893 1.00 PTGS2 (0.63) PTGS2BRD4PTPN5PTPN2CYP11B2
SCHEMBL30407966 1.00 PTGS2 (0.63) PTGS2BRD4PTPN5PTPN2CYP11B2
Water SCHEMBL27498058 0.98 PTGS2 (0.61) PTGS2BRD4PTPN5PTPN2CYP11B2
Hydrogen Sulfide SCHEMBL27800905 0.98 PTGS2 (0.61) PTGS2BRD4PTPN5PTPN2CYP11B2
Phosphine SCHEMBL27888972 0.98 PTGS2 (0.61) PTGS2BRD4PTPN5PTPN2CYP11B2
SCHEMBL29433489 0.98 PTGS2 (0.60) PTGS2BRD4PTPN5PTPN2CYP11B2
SCHEMBL10789751 0.98 PTGS2 (0.60) PTGS2BRD4PTPN5PTPN2CYP11B2
Ethane SCHEMBL27580684 0.96 PTGS2 (0.64) PTGS2BRD4PTPN5PTPN2CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4535 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059683-A Synthetic heat conduction oil and application 中国石油化工股份有限公司 2025-05-30 CN claimed
CN-118879339-A Wide-temperature-range liquid crystal material and preparation method and application thereof 北京大学 2024-11-01 CN claimed
CN-115305066-B Polycyclic aromatic hydrocarbon heat conduction composition 中国石油化工股份有限公司 2024-08-30 CN claimed
CN-115305067-B Synthetic heat conduction oil 中国石油化工股份有限公司 2024-07-23 CN claimed
CN-116948656-B Application of ionic liquid in preparation of fluoroalkyl cyclohexyl biphenyl liquid crystal compounds 河北美星化工有限公司 2024-07-09 CN claimed
CN-118027907-B High-temperature insulating heat conducting oil for energy storage equipment and preparation method thereof 大连天宇热能有限公司 2024-06-14 CN claimed
CN-118027907-A High-temperature insulating heat conducting oil for energy storage equipment and preparation method thereof 大连天宇热能有限公司 2024-05-14 CN claimed
CN-117487523-A Synthetic thermal conductive medium and synthetic method and system thereof 中国石油化工股份有限公司 2024-02-02 CN claimed
CN-117343697-A Thermosensitive composition and production method and system thereof 中国石油化工股份有限公司 2024-01-05 CN claimed
US-11814563-B2 Bioreachable chiral dopants for liquid crystal applications ZYMERGEN INC. (US) 2023-11-14 US claimed
US-4545922-A Liquid crystalline fluorine-containing cyclohexylbiphenyls and dielectrics and electro-optical display elements based thereon MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1985-10-08 US claimed
EP-0051738-B1 CYCLOHEXYL-BIPHENYL DERIVATIVES THAT CONTAIN FLUOR, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING ELEMENT MERCK PATENT GmbH (DE) 1984-07-25 EP claimed
US-4415470-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-11-15 US claimed
US-4398803-A Liquid crystal display element MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-08-16 US claimed
EP-0022183-B1 DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS MERCK PATENT GmbH (DE) 1982-06-23 EP claimed
US-4330426-A Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-18 US claimed
EP-0022183-A2 Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements MERCK PATENT GmbH (DE) 1981-01-14 EP claimed
US-4167504-A PVC plasticized with monocyclohexylbiphenyl SUN OIL COMPANY OF PENNSYLVANIA (US) 1979-09-11 US claimed
US-4154697-A Liquid crystalline hexahydroterphenyl derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1979-05-15 US claimed
US-3981821-A CONDENSATION POLYMERIZATION, AMINO RESINS POLYEPOXIDES FUJI PHOTO FILM CO., LTD. (JA) 1976-09-21 US claimed