Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.45 |
| ▸ | HTR3B | O95264 | 3/20 | 0.45 |
| ▸ | HTR3A | P46098 | 3/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933856 | 0.86 | PPARA (0.54) | PNMTPPARGPPARA | |
| SCHEMBL23933859 | 0.86 | PPARA (0.54) | PNMTPPARGPPARA | |
| SCHEMBL11304092 | 0.81 | PPARA (0.53) | PPARGPPARA | |
| SCHEMBL4780746 | 0.80 | SRR (0.61) | PPARGPPARA | |
| Hydrochloric Acid SCHEMBL5754335 | 0.80 | SRR (0.61) | PPARGPPARA | |
| Hydrochloric Acid SCHEMBL17205769 | 0.80 | PNMT (0.59) | PNMTIDO1CYP3A4AGXTHTR3E | |
| SCHEMBL31324833 | 0.80 | PNMT (0.64) | PNMTIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL15446256 | 0.79 | PNMT (0.51) | PNMTIDO1CYP3A4AGXTPPARG | |
| Hydrochloric Acid SCHEMBL27476980 | 0.78 | PNMT (0.57) | PNMTIDO1CYP3A4AGXTMAOA | |
| Hydrochloric Acid SCHEMBL27478281 | 0.78 | PNMT (0.57) | PNMTIDO1CYP3A4AGXTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160794-A1 | Tachykinin receptor antagonists | ELI LILLY AND COMPANY | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160794-A1 | Tachykinin receptor antagonists | TACR1, TACR2, PROKR1 | PNMT 1318/4885IDO1 554/4885CYP3A4 3742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.