Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107267 | 0.84 | CYP1A2 (0.45) | CYP1A2CYP2A6ATMACHETDO2 | |
| SCHEMBL9227699 | 0.78 | ATM (0.40) | ATMACHEHSP90AA1MAPTHTT | |
| SCHEMBL3264399 | 0.76 | MEN1 (0.47) | CYP1A2ATMACHEHSP90AA1MAPT | |
| SCHEMBL1826895 | 0.76 | CYP2A6 (0.45) | CYP2A6ATMACHEAHRHSP90AA1 | |
| SCHEMBL3732872 | 0.76 | ATM (0.39) | ATMACHEHSP90AA1MAPTHTT | |
| SCHEMBL1771699 | 0.76 | ALDH1A1 (0.45) | ATMACHEHSP90AA1MAPTHTT | |
| SCHEMBL2798405 | 0.76 | KDM4E (0.45) | CYP1A2CYP2A6ATMACHEMAPT | |
| SCHEMBL369538 | 0.76 | CYP2A6 (0.45) | CYP1A2CYP2A6ATMACHEAHR | |
| SCHEMBL20996058 | 0.76 | ATM (0.39) | ATMACHEHSP90AA1MAPTHTT | |
| SCHEMBL11822605 | 0.74 | CA3 (0.31) | CYP1A2CYP2A6ATMACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1172670-C | Liposome composition for improved drug retention | — | 2004-10-27 | — | — | CN | claimed |
| EP-1083881-B1 | LIPOSOME COMPOSITIONs containing a quinolone derivative AND their use as antibacterial agents | ALZA CORP (US) | 2004-08-25 | — | — | EP | claimed |
| EP-0825852-B1 | LIPOSOME DRUG-LOADING METHOD AND COMPOSITION | YISSUM RES DEV CO (IL) | 2004-07-07 | — | — | EP | claimed |
| EP-1176962-B1 | LIPOSOME COMPOSITIONS FOR IMPROVED DRUG RETENTION | ALZA CORP (US) | 2004-02-11 | — | — | EP | claimed |
| CN-1351495-A | Liposome composition for improved drug retention | ALZA CORP (US) | 2002-05-29 | — | — | CN | claimed |
| EP-1176962-A2 | LIPOSOME COMPOSITIONS FOR IMPROVED DRUG RETENTION | Alza Corporation (US) | 2002-02-06 | — | — | EP | claimed |
| EP-1083881-A2 | LIPOSOME COMPOSITION AND METHOD FOR ADMINISTERING A QUINOLONE | ALZA Corporation (US) | 2001-03-21 | — | — | EP | claimed |
| WO-2000066126-A2 | LIPOSOME COMPOSITIONS FOR IMPROVED DRUG RETENTION | ALZA CORPORATION (US) | 2000-11-09 | — | — | WO | claimed |
| EP-0366641-B1 | Novel antimicrobial quinolonyl lactam esters | NORWICH EATON PHARMA (US) | 2000-07-05 | — | — | EP | claimed |
| EP-0997466-A1 | Novel antimicrobial lactam-quinolones | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 2000-05-03 | — | — | EP | claimed |
| US-5434147-A | Bactericides | PROCTOR & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-07-18 | — | — | US | claimed |
| US-5273973-A | Carbapenicillins | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1993-12-28 | — | — | US | claimed |
| EP-0525057-A4 | ANTIMICROBIAL QUINOLONYL LACTAMS | — | 1993-04-07 | — | — | EP | claimed |
| EP-0525057-A1 | ANTIMICROBIAL QUINOLONYL LACTAMS | Norwich Eaton Pharmaceuticals, Inc. (US) | 1993-02-03 | — | — | EP | claimed |
| US-5180719-A | Microbiocides | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1993-01-19 | — | — | US | claimed |
| WO-1991016327-A1 | ANTIMICROBIAL QUINOLONYL LACTAMS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1991-10-31 | — | — | WO | claimed |
| WO-1990004594-A1 | NOVEL ANTIMICROBIAL QUINOLONYL LACTAM ESTERS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1990-05-03 | — | — | WO | claimed |
| EP-0366193-A2 | Novel antimicrobial quinolonyl lactams | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | claimed |
| EP-0366641-A2 | Novel antimicrobial quinolonyl lactam esters | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | claimed |
| EP-0366189-A2 | Novel antimicrobial lactam-quinolones | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | claimed |