Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 6/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 14/20 | 0.42 |
| ▸ | PIK3R2 | O00459 | 12/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6071514 | 0.85 | IKBKB (0.47) | IKBKBPIK3CDPIK3R2 | |
| SCHEMBL6072026 | 0.70 | IKBKB (0.51) | IKBKBPIK3CDPIK3R2PIK3CG | |
| Hydrochloric Acid SCHEMBL7021906 | 0.66 | IKBKB (0.40) | IKBKB | |
| SCHEMBL6071963 | 0.66 | NSD2 (0.51) | PIK3CD | |
| SCHEMBL6071518 | 0.64 | HTR3A (0.45) | IKBKB | |
| SCHEMBL6071597 | 0.63 | IKBKB (0.47) | IKBKBPIK3CDPIK3R2 | |
| SCHEMBL6071657 | 0.62 | ALDH1A1 (0.42) | PIK3CDPIK3R2 | |
| SCHEMBL14491957 | 0.61 | IKBKB (1.00) | IKBKB | |
| SCHEMBL6071662 | 0.61 | CACNA2D1 (0.43) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL20889626 | 0.61 | PDCD1 (0.39) | IKBKBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264460-A1 | 3-Cyanoquinoline inhibitors of Tpl2 kinase and methods of making and using the same | WYETH (US) | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264460-A1 | 3-Cyanoquinoline inhibitors of Tpl2 kinase and methods of making and using the same | TNNI3K, CSNK1A1L, CDKL1 | IKBKB 603/4885PIK3CD 814/4885PIK3R2 982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.