Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638473 | 0.91 | ALDH1A1 (0.65) | ALDH1A1GAAPOLBPTGER4CYP19A1 | |
| SCHEMBL4637749 | 0.88 | ALDH1A1 (0.53) | ALDH1A1GAAPOLBCYP19A1TSHR | |
| Hydrochloric Acid SCHEMBL5794894 | 0.87 | ALDH1A1 (0.52) | ALDH1A1GAAPOLBCYP19A1TSHR | |
| SCHEMBL4638506 | 0.84 | ALDH1A1 (0.47) | ALDH1A1GAAPOLBCYP19A1TSHR | |
| SCHEMBL14144376 | 0.82 | CYP1A1 (0.46) | ALDH1A1GAACDC7POLBCYP19A1 | |
| SCHEMBL4706967 | 0.82 | POLB (0.50) | ALDH1A1GAAPOLBPTGER4TACR1 | |
| SCHEMBL4706776 | 0.82 | ALDH1A1 (0.54) | ALDH1A1GAAPOLBPTGER4CYP19A1 | |
| SCHEMBL4637742 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GAAPOLBCYP19A1TSHR | |
| SCHEMBL4638482 | 0.82 | ALDH1A1 (0.44) | ALDH1A1GAACDC7POLBPTGER4 | |
| SCHEMBL6071885 | 0.79 | ALDH1A1 (0.45) | ALDH1A1GAAPOLBPTGER4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160794-A1 | Tachykinin receptor antagonists | ELI LILLY AND COMPANY | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160794-A1 | Tachykinin receptor antagonists | TACR1, TACR2, PROKR1 | ALDH1A1 1815/4885GAA 1942/4885CDC7 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.