Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 7/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707735 | 0.94 | TACR1 (0.52) | IDH1TACR1PTGER4HTTALDH1A1 | |
| SCHEMBL4708123 | 0.87 | TP53 (0.49) | IDH1TACR1 | |
| SCHEMBL4707843 | 0.86 | EPHX2 (0.48) | IDH1TACR1HTTALDH1A1GAA | |
| SCHEMBL4705917 | 0.85 | IDH1 (0.50) | POLBIDH1TACR1ALDH1A1GAA | |
| SCHEMBL4706969 | 0.85 | CACNA1G (0.49) | IDH1TACR1PTGER4ALDH1A1GAA | |
| SCHEMBL4706714 | 0.85 | TACR1 (0.48) | IDH1TACR1ALDH1A1GAA | |
| SCHEMBL4708362 | 0.83 | ALDH1A1 (0.56) | ALDH1A1GAA | |
| SCHEMBL4707944 | 0.83 | IDH1 (0.48) | IDH1TACR1PTGER4ALDH1A1GAA | |
| SCHEMBL6072058 | 0.82 | ALDH1A1 (0.53) | POLBTACR1PTGER4ALDH1A1GAA | |
| SCHEMBL4638473 | 0.82 | ALDH1A1 (0.65) | POLBPTGER4ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |