Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6071737 | 0.91 | SSTR5 (0.41) | ALDH1A1THRBL3MBTL1SSTR5FFAR4 | |
| SCHEMBL5785108 | 0.88 | FFAR4 (0.35) | ALDH1A1KMT2APOLBFFAR4MAPT | |
| SCHEMBL5783270 | 0.88 | MAPT (0.37) | ALDH1A1SSTR5KMT2APOLBFFAR4 | |
| SCHEMBL6071457 | 0.87 | SSTR5 (0.38) | SSTR5FFAR4 | |
| Hydrochloric Acid SCHEMBL5785102 | 0.87 | FFAR4 (0.35) | ALDH1A1KMT2AFFAR4MAPTKDM4E | |
| SCHEMBL6072275 | 0.86 | CYP4F2 (0.36) | ALDH1A1SSTR5KMT2APOLBFFAR4 | |
| SCHEMBL6072465 | 0.86 | SSTR5 (0.39) | L3MBTL1SSTR5POLBFFAR4MAPT | |
| SCHEMBL6072463 | 0.86 | FFAR4 (0.32) | SSTR5KMT2APOLBFFAR4TSHR | |
| SCHEMBL6071698 | 0.85 | SSTR5 (0.33) | SSTR5FFAR4 | |
| SCHEMBL6072497 | 0.85 | POLB (0.44) | KMT2APOLBMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106048-A1 | Furoisoquinoline derivative and use thereof | PASCALI, PETROS P. (CY) | 2006-05-18 | — | — | US | disclosed |
| EP-1541576-A1 | FUROISOQUINOLINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106048-A1 | Furoisoquinoline derivative and use thereof | PDE3B, PDE2A, PDE3A | ALDH1A1 423/4885THRB 601/4885L3MBTL1 3625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.