Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | NPY1R | P25929 | 13/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072759 | 0.98 | HRH1 (0.58) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6073337 | 0.90 | HRH1 (0.47) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6072979 | 0.88 | HRH1 (0.45) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6072778 | 0.85 | HRH1 (0.43) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6073196 | 0.84 | NPY1R (0.46) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6072623 | 0.84 | NPY1R (0.51) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6072713 | 0.82 | HRH1 (0.43) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL6072800 | 0.80 | TAS1R3 (0.47) | HRH1KCNH2CYP2D6CHRM1NPY1R | |
| SCHEMBL868571 | 0.77 | HRH3 (0.56) | HRH1CYP2D6 | |
| SCHEMBL6072802 | 0.77 | HRH3 (0.57) | HRH1KCNH2CYP2D6CHRM1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006019497-A2 | SLEEP-INDUCING COMPOUNDS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2006-02-23 | — | — | WO | claimed |
| WO-2006019497-A2 | SLEEP-INDUCING COMPOUNDS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2006-02-23 | — | — | WO | disclosed |