Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.51 |
| ▸ | HTR7 | P34969 | 3/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6073412 | 0.99 | HTR1A (0.51) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL6072677 | 0.97 | HTR1A (0.51) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL6072915 | 0.96 | HTR7 (0.50) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL6072924 | 0.88 | HTR1A (0.45) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL6072969 | 0.88 | HTR1A (0.44) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL4522960 | 0.85 | HTR1A (0.61) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL4524619 | 0.84 | HTR1A (0.60) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11173615 | 0.84 | HTR7 (0.69) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL5592219 | 0.82 | HTR7 (0.64) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL5424281 | 0.82 | HTR1A (0.56) | HTR1AHTR7ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006013445-A2 | THIAZOLIDINEDIONE DERIVATIVES AS ALPHA ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-09 | — | — | WO | disclosed |